Jobs for People with MS: National MS Society

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Title: Executive Director , Multiple Myeloma Disease Head

Translational Medicine at BMS Translational Medicine is part of the Global Research and Early Development organization in BMS and leads early stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. The Heme Translational Medicine Disease Team (TMDT) is a late translational group that supports multiple disease areas of interest including Myeloma, Myeloid, Lymphoma, Erythroid disorders, and other hematological malignancies. This group integrates scientific and business insights of multiple functions and leads the development of translational strategies at the franchise level and implements them in project teams to maximize the potential of BMS drugs.

Summary:

Reporting to the VP, Hematology Translational Medicine, the incumbent will be part of the translational group based in Summit NJ and will help develop translational disease and asset strategies in Multiple Myeloma or Myeloid/Erythroid disease areas for assigned programs for approval or life-cycle management of the BMS pipeline. Key responsibility of this role is to lead the Myeloma disease team consisting of a cross functional team of asset and disease scientists with deep disease, drug development and business knowledge for overall translational strategy working closely with discovery and early development teams, late clinical development as well as with a hematology laboratory group.

Technical Skills:

• In-depth understanding of Oncology or Hematological cancers, especially Multiple Myeloma, , clinical landscape, evolving therapy, competitive landscape

• Strong understanding of clinical, translational and mechanistic data with therapeutics development

• Strong background in genetics, cancer biology and/or immunology

• Strong background in strategy development preferably in hematology

• Understanding of late-stage drug and translational development process • Proven track record of drug submissions, approvals, regulatory interactions and label negotiations

• Proven ability to work with global disease teams to develop strategies to support life cycle management efforts tailored to regional markets (i.e, US, EU, CAN) bms.com/careers

• Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses • Proven scientific/project leadership expertise (working in teams, managing people/projects)

• Ability to synthesize complex scientific and business problems into strategy and tactics

• Basic understanding of IP, contracting terms and provisions

Responsibilities:

In coordination with Head of Strategy and Execution, builds disease area specific long term translational strategy and implementation across portfolio:

• Leads the development of disease, portfolio, or asset specific translational annual goals and objectives for the Heme TMDT (for internal /external, translational collaboration, compound specific plans etc), open research questions, and is accountable for their progress monitoring in association with Heme TMDT asset and disease scientists

• Assists in developing and maintaining group budget and workforce plan

• Represents Translational Medicine (TM) in cross-functional Strategy and Global Project Teams

• Interfaces with commercial including early commercialization group and Medical Affairs to provide scientific support for cross-functional TM goals

• Assists in managing key strategic and/or collaborative projects along with TM scientists

• Supports regulatory submissions, regulatory interactions, writes translational sections for regulatory response and answers to regulatory queries for the TM group

• Communicates regularly and prepares and makes presentations within the department and externally as required

• Participates in translational research with the Heme TMDT Lab

• Oversees genomic analyses from human clinical samples, cell screens (ie, for resistance mechanisms, PD, biomarkers) and clinical trial support (defined clinical experiments from the development teams). This includes development of high dimensional bioinformatics in collaboration with the Informatics and Predictive Sciences group

• Responsible for delivery of Clinical PD or Biomarker assays, translated from discovery (if applicable or appropriate) or developed specifically for early clinical use, assessing feasibility and applicability for companion diagnostics

• Application of model systems (in collaboration with the disease biology and in vivo pharmacology groups) beyond those routinely employed by discovery teams that aid in patient stratification/response and compound use, either in-house or as a collaboration • Participates in formulating disease area strategy for target selection and validation

• Evaluating, in conjunction with BD and established teams, the potential for in-licensing opportunities that may include potential therapeutics, emerging technologies, processes or capabilities that will enhance our Drug Discovery and Early Development efforts

• Be part of the team responsible for establishing key alliances with academic centers, co-operative groups and government agencies for cost effective implementation of BMS early and late development strategy

• May perform advisory and mentoring role for junior scientists • Supports MRD efforts across Heme area

• Liaises with key BMS Research and Early Development thematic centers of excellence to help formulate and execute on new hypotheses driving new clinical biomarker assays for unmet need segments, disease strategy for new targets and development candidates and ensure seamless transition of patient selection strategies beyond Phase 1

• Serves as translational representative on BMS cross functional Disease Strategy Team and interfaces with commercial, clinical, Project leadership and regulatory teams to define patient segments of unmet need based on rapidly evolving clinical programs and commercial landscape

• Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statistician

Summary:

The candidate will be at the interface with asset, disease and lab teams, with the aim of providing the successful implementation of translational strategies in BMS pipeline development

Qualifications:

• MD/PhD in Hematology/Oncology or related field with minimum 12-15 years in industry or industry plus academic setting

• Track record in large and small companies, leading innovative efforts to deploy technologies and assays for enhanced translational capabilities

• Excellent communication, managerial and scientific qualities are expected

• Ability to interact effectively across boundaries using influencing and relationship building skills.

• Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.

• Other Attributes: A problem solver who creatively and knowledgably transcends departmental function to act as a resource to entire research effort and senior managers in development.

• Identifies issues early and proposes innovative solutions.

• Communicates within the larger organization and external community.

• Provides expert guidance to multi-disciplinary teams and senior management.

• A leader whose scope of influence stretches across BMS.

• A leader who influences external scientific community.

• Expertise in the integration of preclinical research and clinical drug development

• Ability to lead basic research programs as well as development and execution of clinical correlative science strategies

• Management experience with the ability to set priorities, direct projects and implement complex strategies and work on cross-functional team

• Highly effective teamwork and interpersonal skills and the ability to work across numerous scientific disciplines

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol-Myers Squibb

Req Number: R1580942

Updated: 2024-05-15 02:20:08.694 UTC

Location: Summit West-NJ

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.